GW501516 10 Cardarine


In bodybuilding, cardarine offers two key advantages. Fat Burning: It exhibits fat-burning properties, aiding individuals in their weight loss journeys. Improved Workout Performance: Cardarine enables athletes to engage in more intense and longer workouts without experiencing excessive fatigue.

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GW501516 10 Cardarine

Known names: Endurobol, GSK-516, GW1516, GW-501, GW-501516, GW 501516, GSK516, GW-501516 Cardarine, Cardarine SARM, PPAR-delta agonist.


Despite its classification as a PPAR-delta agonist (peroxisome proliferator-activated receptors), cardarine (GW 501516) is often mistakenly considered a SARM (selective androgen receptor modulator). Just as a tomato is commonly sold as a vegetable, cardarine is commonly marketed as a SARM. Cardarine was originally developed for its health benefits, functioning by activating pathways that are typically stimulated during exercise. In this informative article, we will provide comprehensive insights into this powerful compound in easily understandable language.

The discovery of cardarine can be attributed to research collaborations between GSK and Ligand Pharma in the early 1990s. Initially, it underwent phase 1 trials in 2000 to treat lipid strain, but its development was halted in 2008. Nevertheless, cardarine is currently used as a research compound, while athletes utilize it for performance enhancement and fat burning purposes.

Cardarine was primarily developed to address obesity, diabetes, lipid strain, and cardiovascular issues. In fact, individuals who undergo blood work will notice remarkable improvements in lipid strain and substantial enhancements in cholesterol levels upon cardarine usage.

Cardarine is popular among athletes participating in various sports. For instance, endurance athletes can enhance their exercise capacity by combining this PPAR agonist with the AMP analog drug AICAR or using cardarine alone. This combination allows athletes to sustain higher RPMs during runs without reaching their maximum heart rate, enabling them to extend their endurance without becoming easily fatigued. From personal experience, I can attest that cardarine can shave off 30-45 seconds from a 5K race time when used in the lead-up to the event.

In the realm of bodybuilding, cardarine offers two key advantages:

  1. Fat Burning: It exhibits fat-burning properties, aiding individuals in their weight loss journeys.
  2. Improved Workout Performance: Cardarine enables athletes to engage in more intense and longer workouts without experiencing excessive fatigue.

During weightlifting sessions, cardarine users may notice that their heart rate remains elevated, allowing them to achieve more repetitions before reaching failure. Additionally, shorter rest periods between sets can be taken. Bodybuilders who engage in post-weight training cardio workouts will also appreciate these benefits.

Cardarine has been widely abused by athletes, leading to its ban by the World Anti-Doping Agency (WADA) in 2009, categorizing it as a “hormone and metabolic modulator.” Several cyclists have faced repercussions for using cardarine, including Valery Kaykov from Russia and Miguel Ubeto from Venezuela. Notably, Elena Lashmanova of Russia, the world record holder in the 20M race walk, tested positive for cardarine.

In relation to obesity, cardarine can reverse metabolic abnormalities in obese and pre-diabetic individuals by promoting fatty acid oxidation. It achieves this by increasing glucose uptake in skeletal muscle tissue, shifting the body’s metabolism to prioritize fat burning for energy instead of muscle or carbohydrates. Remarkably, cardarine achieves these effects without causing a drop in blood sugar levels, unlike diabetic medications. Even when mice were fed a high-fat diet, cardarine prevented obesity, demonstrating its efficacy.

Cardarine can be stacked in several ways:

  1. Endurance: For the ultimate endurance stack, consider combining cardarine with AICAR and/or Equipoise. This combination can transform you into a high-performing athlete.
  2. Fat Loss: For a potent cutting stack, cardarine can be stacked with S4 (Andarine).
  3. Anabolic Steroid Stack: When using moderate doses of anabolic steroids or harsh compounds like trenbolone, cardarine can complement lipid profiles and enhance cardiovascular endurance. It is particularly suitable for stacking with trenbolone, which often leads to rapid fatigue.
  4. Post Cycle Therapy (PCT) or Bridge: Since cardarine is not hormonal, it does not cause suppression, making it safe to use during PCT or bridging cycles. It helps preserve lean muscle mass and improve workouts during these periods.
  5. SARMs Triple Stack: If your goal is body recomposition, cardarine synergizes well with S4 and MK-2866.

Side Effects

Cardarine is generally well-tolerated with rare side effects. However, like any substance, it should be used at the appropriate dosage and cycled on and off. As it is not a hormone, there is no need to be concerned about post-cycle therapy or suppression.


The half-life of GW501516 (cardarine) is approximately 20-24 hours. This means that a once-daily dose is sufficient. Some athletes prefer taking the full 20 mg dose one hour before their workout session, while others divide the dose equally between morning and evening. It is recommended to administer the liquid form of cardarine orally, followed by ingestion of juice or water to facilitate consumption.


1 Box of 2x 25Tablets, 10mg per Tablet.


Keep the product stored below 30°C.
Protect it from light exposure and avoid freezing.

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